Of ASC family members (Figure 3G), expression of ACSL1 mRNA up‐regulated in mucous epithelia of COPD and IPF, ACSL3 in ATI of COPD, basal epithelia of IPF, ciliated epithelia of COPD and IPF, club epithelia of IPF, Goblet cells of ADC, mucous epithelia of COPD and IPF and ACSL4 in ATI and ATII of IPF. Here, ACSL4 is linked to chronic obstructive pulmonary disease.