AKT1 and neoplasm: Consistently, Akt activity restrained by MK2206 also reversed the transactivation of NF‐κB signalling (Figure 5C), increased the protein expression levels of p‐Akt and p‐IκBα, but decreased IκBα level (Figure 5D), and suppressed the tumour cell repopulation of reporter cells induced by feeder cells (Figure 5E).