Caspase 3 activates the iPLA2‐arachidonic acid‐PGE2 axis and PKCδ/Akt/VEGF‐A axis and promotes apoptotic extracellular vesicle secretion enriched with various components of spliceosomes to enhance cell death‐induced tumour cell repopulation.8 The gene discussed is PRKCD; the disease is neoplasm.