Interestingly, the elimination of radiation-induced senescence in astrocytes using an inhibitor of Bcl-2 attenuated glioblastoma recurrence [36, 40, 41], while injecting irradiated, senescent human glioblastoma multiforme cells into an immunocompromised mouse resulted in faster tumor growth compared with non-irradiated, non-senescent cells [42]. This evidence concerns the gene BCL2 and glioblastoma.