When comparing the 435 patients with hyperbilirubinemia (grades 1-4) during induction/consolidation to the 215 patients with normal bilirubin levels, the five loci most associated with this phenotype were the UGT1A gene cluster, MARK2P5, SULF2, MIR924HG and USH2A (Suppl. This evidence concerns the gene MARK2P5 and Hyperbilirubinemia.