Out of 544 patients 62 (11%) were homozygous for either UGT1A1*28/*28 or *37/*37 – this cannot be differentiated by our assay – and had the highest rate and risk of hyperbilirubinemia (89% compared to 58% for *1/*1; OR in comparison to *1/*1 5.8; 95% CI = 2.5-13.3; P = 3.3 × 10− 5) (Suppl. Here, UGT1A1 is linked to Hyperbilirubinemia.