Many Bcl-2 protein family inhibitors have been developed over the past years, including venetoclax (ABT-199), navitoclax (ABT-263), obatoclax (GX15-070), oblimersen sodium (G3139), etc., and are mostly used in leukemia, lymphomas, and other hematological malignancies [9]. This evidence concerns the gene BCL2 and hematologic disorder.