Similarly, Western bloting (Fig. 7c), ELISA (Fig. 7d) and flow cytometry assays of cell lines (Fig. 7c) and tumor single cell suspension (Fig. 7e) demonstrated that exogenous expression of full-length Neto2 plasmids recovered the capability of sLRIG3 to attenuate the tilt towards an M2-dominant TAM population compared with TAMs transfected of empty or CUB1-deleted Neto2 plasmids. The gene discussed is NETO2; the disease is neoplasm.