Furthermore, under α‐melittin‐NP treatment, the concentration of IL‐4 in the AD lesions decreased by 91.9% (Figure 5F), the concentration of IL‐6 decreased by 59.7% (Figure 5G), and the concentration of TNF‐α decreased by 40.8% (Figure 5H). The gene discussed is TNF; the disease is Alzheimer disease.