During the development of AD, thymic stromal lymphopoietin (TSLP) released by epidermal cells induces the strong differentiation of Th2 cells by stimulating DC activation.[35] In our OXA‐induced AD‐like model, the TSLP expression in α‐melittin‐NP‐ treated group decreased by 79.5% and was not significantly different from that in untreated normal skin (Figure 5K). This evidence concerns the gene TSLP and Alzheimer disease.