Furthermore, no significant differences were found in LIMp27 expression between COAD and colon adenomas (pre‐neoplastic colon lesions), whereas LIMp27 expression was upregulated in colon adenomas compared with normal colon epithelia (Figure 1f), suggesting that LIMp27 upregulation is commonly an early event during COAD development. This evidence concerns the gene LINC01356 and colon adenoma.