In this study, twelve variables were identified as significant predictors of OS and RFS, including multiple tumor numbers, tumor size > 5 cm, Edmonson grade III-IV, MVI positivity, BCLC-C stage, tumor satellite focus positivity, macrovascular invasion, serum albumin, AST > 40 U/L, NEUT ≥ 3.82 x109/L and AFP > 400 ng/ml. Here, AFP is linked to neoplasm.