Similar to the mesenchymal subtype from the original TCGA study of ovarian cancer, S‐ECM shows upregulation of genes such as COL5A2, COL1A1, COL3A1, THBS2, COL11A1, COL6A3, and MMP2 that are involved in epithelial‐to‐mesenchymal transformation (EMT) processes, metastasis, and chemoresistance [48, 49, 50, 51, 52]. This evidence concerns the gene MMP2 and ovarian carcinoma.