MAGEL2 and Intellectual disability: Moreover, owing to an increased prevalence of intellectual disability, autism spectrum disorder (ASD) and disrupted social behaviors in people with SYS and MAGEL2-related disorders compared to PWS (McCarthy et al., 2018; Patak et al., 2019; Marbach et al., 2020), evaluating the consequences of truncated MAGEL2 in species that enable the study of more complex behavioral patterns could provide deeper insight for the study of these specific phenotypes.