All compounds are evaluated under normoxic and anoxic conditions against different cell lines such as MRC-5 (human foetal lung fibroblast cells, normal lung cell), HCT-116 (human colorectal cancer cell line, which does not express hCA IX in response to anoxia), MDA-MB-231 (human breast carcinoma cell line, CA IX negative), and HT-29 (human colon carcinoma cell line, overexpressing high amounts of CA IX), but without any data regarding the binding affinity against hCA IX. This evidence concerns the gene CA9 and colorectal cancer.