CENPM and nonpapillary renal cell carcinoma: As CENPM was differentially expressed in kidney cancer samples and paraneoplastic samples, we demonstrated the effect of high CENPM expression on survival outcome in ccRCC patients by means of Kaplan-Meier curves, and the results revealed that CENPM upregulation was strongly associated with worsening overall survival (OS), DSS and progression-free interval (PFI) (Fig. 4A-C).