The SCLC lines exhibited variable MHC-I induction following EZH2i or Menin inhibitor (MENi) treatment and in a line that showed little response to either inhibitor alone, combined treatment enhanced IFN-γ induced tumour MHC-I expression and cytokine production from co-cultured T-cells (Extended Data Fig. 5h/i). This evidence concerns the gene MEN1 and small cell lung carcinoma.