F2 and Sepsis: Therefore, in contrast to other DIC-screening tools like the ISTH overt-DIC score [6] and the Japanese Association for Acute Medicine (JAAM) score [7], the SIC score only relies on three components: (1) an adapted Sequential (sepsis-related) Organ Failure Assessment (SOFA) score, (2) the platelet count, and (3) the international normalized ratio (INR; or the prothrombin time [PT]) [4, 8].