After stratified analysis according to sex, age, diabetes and hypertension, it was found that the negative correlation between serum albumin level and CHD risk was statistically significant in women [OR = 0.948, 95% CI = (0.911, 0.987), Table 3], the participants aged 60 and over [OR = 0.963, 95% CI = (0.940, 0.987), Table 3], participants without diabetes [OR = 0.969, 95% CI = (0.939, 0.999), Table 3] and those with hypertension [OR = 0.962, 95% CI = (0.938, 0.986), Table 3]. The gene discussed is ALB; the disease is coronary artery disorder.