On the contrary, CD123-IgG1+ was completely inactive on OCI-AML2, OCI-AML3, THP-1 and SKM-1 CD64-positive cell lines, and showed limited activity on NB-4 and MV4-11 compared to the NKCE that was significantly highly superior to CD123-IgG1+ (Extended Data Fig. 1c, P < 0.0001), confirming with AML cell lines the results observed on primary AML samples. This evidence concerns the gene IL3RA and acute myeloid leukemia.