IL3RA and acute myeloid leukemia: 8 and 9) and one CD64-negative (AML no. 10) (Extended Data Fig. 2a,b), further confirmed that, unlike CD123-IgG1+, which was active only against the CD64-negative sample (AML no. 10), CD123-NKCE mediated the autologous activation of NK cells from the three patients against their own blasts regardless of CD64 expression (Extended Data Fig. 2b).