The most frequent in the ACMG SFs were gene/disease and frequency TTN DCM (four times); KCNQ1 LQTS (three times); MYBPC3 HCM (two times); TMEM43 arrhythmogenic right ventricular cardiomyopathy (two times); PALB2 HBC (two times); and RYR1 MH (two times). The gene discussed is MYBPC3; the disease is familial dilated cardiomyopathy.