In the latest study, ITGB2-AS1 had been confirmed higher expression in KIRC tissues and associated with prognosis with clear cell renal cell carcinoma.17 In this study, the results from GEPIA database and clinical data showed that the expression of ITGB2-AS1 in KIRC tissues was significantly higher than that in the adjacent tissues and the higher expression of ITGB2-AS1 was closely related to the poor prognosis of KIRC patients. Here, ITGB2 is linked to clear cell renal carcinoma.