,38 Although the CML LSCs can be robustly characterized as Lin−CD34+CD38−CD90+CD93+;39 AML LSCs can phenotypically be CD34−CD38−, CD34+CD38−, CD34+CD38+, or CD34−CD38+, and sometimes all 4 are present in individual patient samples.39 This evidence concerns the gene CD38 and acute myeloid leukemia.