WT BAC16 KSHV latency also induced LC3 puncta formation and phosphorylation of Ser90 of Beclin, consistent with our result using the KSHV.219 virus, whereas infection with delB BAC16 virus failed to enhance autophagic flux or phosphorylation of Beclin at Ser90 (Fig 7C and 7D). The gene discussed is MAP1LC3A; the disease is infection.