Consistently, purified exosomes from a rhabdomyosarcoma cell line that is CAR negative but DAF positive RD cells (RD-exo), failed to bind with CVB3 virions, in contrast to the exosomes from CAR-positive Caco-2 cells (Caco-2 exo), as indicated by an immunological pull-down assay (Fig 5K and 5L). Here, CD55 is linked to rhabdomyosarcoma.