Also, the relationships between some cancer suppressor genes (such as Tumor Protein P53 (TP53, P53), APC Regulator of WNT Signaling Pathway (APC), and Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha (PIK3CA)) mutation and prognosis and TIL infiltration features have not been fully analyzed. Here, PIK3CA is linked to cancer.