For example, high levels of plasma IL‐1β were detected in patients with atherosclerosis, which are positively correlated with the severity of the disease (Qamar & Rader, 2012) and inhibition of IL‐1β‐induced signal transduction alleviates atherosclerosis (Libby, 2017; Ridker et al., 2017). Here, IL1B is linked to atherosclerosis.