In human hepatocellular carcinoma (HCC), hypoxia inducible factor-1α (HIF-1α) induced YTHDF1 expression was positively associated with hypoxia-induced autophagy and autophagy-related HCC progression via promoting the translation of autophagy-related genes ATG2A and ATG14 in an m6A-dependent manner 79. Here, HIF1A is linked to hepatocellular carcinoma.