Taken together, the results indicated that co-injection of anti-BGN HGC27+CAFLCs/sh-control rescued the inhibitory effect of knockdown BGN expression on subcutaneous tumor growth or intraperitoneal tumor dissemination, while co-injection of anti-BGN HGC27+CAFLCs/sh-FAP eliminated the rescued effect. The gene discussed is BGN; the disease is neoplasm.