METTL14 and neoplasm: The mRNA expression levels of YTHDC2, YTHDF1, YTHDF3, IGF2BP1, and IGF2BP3 were significantly increased in tumour tissues compared with paired normal breast tissues, while the METTL14, WTAP, FTO, and IGF2BP2 expression levels were significantly decreased in tumour tissues (Figure 1A).