CD274 and neoplasm: Xuejun Wen et al. proved that 2-[18F]FDG treatment could upregulate the expression of PD-L1 on MC38 tumors, and the combination of 2-[18F]FDG (37 MBq) and anti-PD-L1 mAb improved the anti-tumor efficacy and prolonged the overall survival 97.