Functionally, CTAR-1 and CTAR-2 domains of LMP1 can activate a number of signaling cascades, including the PI3K-AKT, NF-κB, MAPK, JNK, JAK-STAT and p38/MAPK pathways 15, which confers to tumor transformation, immune suppression and inflammatory responses. Here, PDLIM7 is linked to neoplasm.