These results indicate that in this genetic epilepsy het Gabrg2+/Q390X KI mice, epileptic SWD preferential incidence during NREM sleep period is very similar to sleep preferential incidence of epileptic activity in human Dravet syndrome patients. This evidence concerns the gene GABRG2 and encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy.