S-GFAP levels did not differ between IIH patients and HCs (median and IQR, 51.9 (36.0–70.2) vs. 53.7 (40.1–68.6), p = 0.72, Mann-Whitney test, Fig. 3A), whereas CSF-GFAP levels (2306 pg/ml (1339–3770) vs. 1648 pg/ml (1042–2015), p = 0.0028, Fig. 3B) and QGFAP were higher in IIH patients than in HC (46.3 (24.6–73.3) vs. 32.0 (14.6–49.3), p = 0.009, Fig. 3C). Here, GFAP is linked to pseudotumor cerebri.