The results of univariate analysis showed that patients with higher BMI (P = 0.004), hypertension history (P = 0.024), lower serum prealbumin level (P = 0.032), lower serum albumin level (P = 0.001), a thicker pancreas (P < 0.001) and a soft pancreas (P = 0.001) were more likely to develop CR-POPF (Table 2). The gene discussed is TTR; the disease is hypertensive disorder.