CAG25 treatment exclusively facilitated DMD exon 78 and BIN1 exon 11 inclusions in these DM1 myotubes without exerting any effects on the expressions of MYH8, DMPK and MBNL1 (Fig. 4e,f, Supplementary Fig. S7f. This evidence concerns the gene DMPK and myotonic dystrophy type 1.