Dastidar et al.50 reported observing SERCA1 splicing defect in DM1-hiPSC-derived myotubes established via mesoangioblast-like cell induction in a six week culture, and thus long-term culture seems to be required for recapitulation of the SERCA1 splicing defect. Here, ATP2A1 is linked to myotonic dystrophy type 1.