In accordance with our observations regarding the patterns of the kinetics, in deceased patients, the mean (± SE) serum MIF level increased from 2997 ± 373 pg/ml on day 0 to 4394 ± 646 pg/ml on day 4, whereas in the sepsis survivors serum MIF decreased from 3137 ± 576 to 2587 ± 384 pg/ml during the same time interval (Fig. 4A). Here, MIF is linked to Sepsis.