In addition, 710 differential m6A-methylated genes in BMSCs were identified in the T2DM group when compared with the control using the array analysis; of which 38 were m6A hypermethylated genes (including LRIG3, BICD2, KLF12, ZFYVE19, and RPUSD4) and 666 were m6A hypomethylated genes (including LURAP1L, TRIB3, RCAN1, PRPSAP1, and RRAGC). The gene discussed is RPUSD4; the disease is type 2 diabetes mellitus.