GDF11 and type 2 diabetes mellitus: On the contrary, the m6A methylation levels of ADNP, GDF11, and RGS2 were significantly downregulated in the T2DM group when compared with the control group (Fig. 3b–d), and the mRNA levels of the ADNP and GDF11 were decreased in accordance with the m6A single nucleotide array results (Fig. 3f, g), and there was no significant difference in the mRNA levels of the RGS2 (Fig. 3h).