But no study has beenconducted to investigate the effects of M. arvensis on PCOS.Regarding the high prevalence of PCOS and complications, and failure of chemicaltreatments in these patients, we investigated the impact of M.arvensis hydroalcoholic extract on LH and FSH hormones in blood, aswell as the expression of Cyp17 and Ptgs2 genesand antioxidant capacity of ovary in a PCOS rat model. The gene discussed is PLOD1; the disease is polycystic ovary syndrome.