Because PGE2 induces CC chemokine receptor 7 (CCR7) expression [31, 32] and CCR7 has a critical role in the migration of myeloid cells from the skin to draining LN [44–47], we evaluated the effect of malnutrition and PGE2 on CCR7 receptor expression and its role in cell trafficking from skin to spleen. The gene discussed is CCR7; the disease is malnutrition.