TSHR and Graves disease: Graves’ disease is an immune system disorder that results in an unregulated andoverproduction of thyroid hormones due to circulating antibodies in the blood.1,2,3 The antibodies produced bind to the thyrotropin receptor and activateglandular function, resulting in hyperthyroidism.2 Graves’ disease leads to major cardiovascular and psycho-cognitivecomplications if left untreated, thus contributing to significant morbidity and mortality.3,4