However, MAP2‐ and GFAP‐positive cells in AD‐derived 3D spheroids (cell line ID: ax0112) differed morphologically and in their spatial distribution compared to healthy 3D spheroids (cell line ID: ax0015); MAP‐positive cells had shorter dendrites and GFAP‐positive cells had more intense GFAP expression (Figure 4B). Here, MAP2 is linked to Alzheimer disease.