Receiver operating characteristic analyses were performed to determine the area under the curve (AUC), optimal cut-off value, sensitivity and specificity values of age, ADMA, SDMA, L-NMMA, NLR, CRP, D-dimer, fibrinogen, ferritin, total protein, albumin in correlation with COVID-19 severity (Table 4 and , Figure 2). The gene discussed is CRP; the disease is COVID-19.