Out of the 18 genes that were reported as differentially expressed (five downregulated and 13 upregulated) in the blood of breast cancer cases compared to controls by Yang et al.[57] [Supplementary Table 17], three (APOB, SLC3A2, CST3) were differentially expressed in breast cancer tissues of cases compared to control in at least two studies. Here, CST3 is linked to breast carcinoma.