We next compared the PTK gene expression profiles of leukemic cells from pediatric and adult KMT2A/MLL-R+ AML cells to the PTK gene expression profiles of AML cells without KMT2A/MLL rearrangements from the corresponding control AML patients in the “other” categories (Children, N = 190; Adults, N = 504). This evidence concerns the gene PTK2B and acute myeloid leukemia.