Furthermore, CDDP-resistant GC cells that up-regulated SNHG6 and circ_AKT3 expression could regulate CDDP resistance and GC progression via sponge miR-1297 and miR-206, respectively, indicating that targeting SNHG6 and circ_AKT3 may be a promising option to address GC chemoresistance [166, 168]. The gene discussed is SNHG6; the disease is gastric cancer.