SIRT1 and metabolic dysfunction-associated steatotic liver disease: In a recently conducted investigation of risk variables for NAFLD in lean Chinese adults, investigators found no genotypic significant differences in common SNPs (sirtuin 1 (SIRT1) rs2273773, APOC3 rs2070666, PNPLA3 rs738409, PNPLA3 rs738408, PNPLA3 rs4823173, PNPLA3 rs2072906, angiotensin II receptor type 1 (AGTR1) rs5186, and AGTR1 rs440881) between lean subjects with and without NAFLD [44].