Similarly, as shown in Fig. 5C and Fig. S4C, NOX4 expression levels were positively associated with 4 types of infiltrating immune cells, including cytotoxic T cells, macrophages (Cor. = 0.23), monocyte cells (Cor. = 0.26) and NKT cells (Cor. = 0.24) and negatively associated with 3 types of infiltrating immune cells, including CD4 T cells, CD4 naïve T cells (Cor. = −0.27) and CD8 T cells in GBM. This evidence concerns the gene CD4 and glioblastoma.