As shown in Fig. 6 and Fig. S4, among the 166 GBM samples and 166 LGG samples analyzed for cytokine and MHC expression, the expression of CCL2 and HLA-E was most significantly positively correlated with the NFE2L2. For receptors, immuno-inhibitors, and immuno-stimulators, the expression of immune factors is different in GBM and LGG. This evidence concerns the gene HLA-E and glioblastoma.