CD4 and neoplasm: Spearman correlation analysis revealed that the high-risk group was strongly linked to the tumor-infiltrating immune cells, including T cell CD4 + Th1, Macrophage M0, Cancer-associated fibroblast, T cell CD4 + Th2, common lymphoid progenitors, uncharacterized cells, T cell CD4 + memory activated and neutrophils (Supplementary Fig. 1).