MKI67 and neoplasm: This resulted in a moderately predictive model including three variables (lymph node status at diagnosis, Ki67 score evaluated by IHC of the patient’s diagnostic biopsy, and % tumor volume reduction by ultrasound following AC) with the area under the receiver operating characteristic (ROC) curve equaling 0.7, a positive predictive value of 0.42, and a negative predictive value of 0.87 (Fig. 4).