Angiomatosis is a benign vascular lesion that most commonly affects females during the first 2 decades of life.[1] It can affect large segments of the body in a contiguous manner by involving several different tissue types and anatomical sites, although it usually involves the lower extremities.[1–4] The etiology is congenital or acquired, with the former being phosphatase and tensin homolog (PTEN)/ phosphoinositide 3-kinases (PI3K) mutations or associated with Klippel–Trenaunay syndrome, Sneddon syndrome, or Gorham disease. Here, PTEN is linked to Gorham-Stout disease.