Furthermore, 15 cell component entries included endoplasmic reticulum lumen, vesicle lumen, ruffle, multivesicular body, internal vesicle lumen, basal plasma membrane, TRAF2–GSTP1 complex, Shc–EGFR complex, basal part of the cell, germinal vesicle, phosphatidylinositol 3-kinase complex, and class IA (see Table S5, Supplemental Digital Content, http://links.lww.com/MD/I66, which illustrates the Go and KEGG analysis of potential targets related to occurrence and development of BC). Here, SHC1 is linked to breast cancer.