Based on the KEGG analysis, we screened 25 pathways that corresponded to 26 protein targets (Fig. 5 shows the top 20 according to P-value < .05), including pathways in cancer, epithelial cell signaling during Helicobacter pylori infection, prostate cancer, nitrogen metabolism, PI3K–Akt signaling pathway, proteoglycans in cancer, estrogen signaling pathway, fluid shear stress and atherosclerosis, breast cancer, focal adhesion, and pancreatic cancer. The gene discussed is AKT1; the disease is Familial prostate cancer.