In the TIMER2.0 database, compared with normal tissues, HENMT1 in head and neck cancer tissues was significantly up-regulated (P < .05), and ZNF347, S100A8, TMEM144, TRPS1, and CGNL1 were significantly down-regulated (P < .05, Supplemental Digital Content [Fig. S7, http://links.lww.com/MD/I102]). This evidence concerns the gene HENMT1 and head and neck cancer.