Studies have shown that inhibiting the expression of S100A8 and S100A9 in cancer cells can significantly reduce the migration and invasion of tumor cells during culture.[27] ZNF347 is the encoded gene of Zinc finger protein 347.[28] TMEM144 is a gene encoding Transmembrane protein 144.[29] TMEM192 is a gene that encodes Transmembrane protein 192.[30] However, there has been little research on the correlation between CGNL1, LCE3A, ZNF347, TMEM144, TMEM192, and cancer. The gene discussed is S100A8; the disease is cancer.